TL;DR
- Secure the Hip Pouch immediately after elevator exit for inventory expansion
- Use high-caliber weapons against Pale Head zombies to prevent regeneration
- Collect Explosive A before descending into warehouse areas
- Navigate shelf gaps carefully while managing multiple enemy types
- Locate the hidden Charle Doll collectible during environmental progression
After departing the elevator, proceed beyond the secondary lift mechanism to discover a forklift positioned just ahead, accompanied by a restorative green herb. Ascend to the upper level where a secure chamber houses a valuable Hip Pouch for inventory capacity enhancement; simultaneously examine the workstation to obtain the Elevator Notice file containing critical operational details.
Upon entering the warehouse complex, prioritize securing Explosive A before descending to lower levels; this crucial resource rests atop debris piles adjacent to the railing breach. Your primary objective involves locating three electrical fuses to reactivate power systems. The initial fuse resides near the first generator platform; exercise extreme caution when approaching as a resilient “Pale Head” zombie will ambush you. These regenerating adversaries require high-impact weaponry like shotguns or magnums for permanent elimination—conventional firearms prove ineffective. Descend via ladder from the generator station, then proceed westward into container units to discover handgun ammunition reserves.
Continue advancement until encountering obstructed pathways. Neutralize the pair of zombie canines that materialize, followed by confronting an additional undead threat ahead. Manipulate shelving units to create passageways while collecting the therapeutic red herb located at ground level upon clearing the gap. Additionally, scan the right-side shelving as you emerge from the cramped corridor to spot a concealed Charle Doll collectible, easily missed during tense combat situations.
Upon entering the laboratory complex, immediately turn left to locate the essential Weaponry Authorization Request file positioned on the main desk, accompanied by gunpowder supplies on an adjacent rolling cart. Activate the specialized machinery to obtain the Capture Syringe device; thorough examination converts this item into the crucial Antigen Sample. Critical warning: retrieving the syringe triggers a reanimation sequence where one corpse rises as an aggressive zombie. Exit Lab A through the distant doorway to discover handgun ammunition in the subsequent chamber and a collectible Charle Doll near the crate obstructions.
Descend the staircase carefully as a newly spawned Pale Head enemy will drop from the suspended packages above. Proceed through the rear exit to access the server facility featuring additional staircases. Navigate around the right server bank to uncover a weapon case containing acid rounds ammunition. Upon entry, locate medicinal red herb in the left corner, with additional gunpowder available on a table near the laptop workstation. Adjacent to the doorway’s right side, discover the Scientist’s Dying Message file beside a deceased researcher.
Reach the staircase base and maneuver toward the power generation unit. Eliminate the pursuing zombie creature, then investigate the large computer server’s opposite side to find a medical case containing first aid spray. Activate the substantial red mechanism to restore power to the massive door across the chamber. Essential preparation: if acid rounds are unavailable, craft them immediately. Locate Explosive B resources ahead if material shortages occur.
Thoroughly search behind the initial specimen container featuring the large cardiac organ to discover a case containing Explosive B. The elevator transports you to an elevated catwalk; during advancement, zombie forces emerge from the forward doorway, comprising one Pale Head, two mutated specimens, and one standard zombie. Beyond this hostile group lies additional Explosive B ammunition.
Enter the Incubation Laboratory, neutralizing the corner-positioned zombie threat. This chamber houses the Liquid-Filled Test Tube; examination transforms it into the Adjuvant Sample. Combine this with your Antigen Sample to produce the Vaccine Base. Additional discoveries include Explosive A in a corner case, gunpowder near adjacent sample tubes, and the Expression of Concern file on the desk below the distinctive Mega Man poster.
During departure, the observing Hunters breach their containment tubes. Initial engagement involves two specimens, with a third joining subsequently. Deploy acid rounds to degrade their defenses, then eliminate them using shotgun weaponry (or preferred alternative arms). After defeating all three creatures, proceed to the vaccine synthesis apparatus and utilize the Vaccine Base. Configure temperature settings to Med, High, Low progression to create the functional Vaccine.
Conduct comprehensive room inspection to acquire multiple resources: flame rounds, explosive rounds, high-grade gunpowder, and first aid spray. The destructible wooden container also houses Explosive B ammunition. On the wall adjacent to the exit, locate the Disposal Center file. Exit onto the extensive catwalk and turn left to discover additional flame rounds, then proceed toward the staircase. Before ascending, perform essential equipment assessment: carry sufficient medical supplies plus maximum grenade launcher ammunition capacity. Approximately 10+ additional magnum rounds significantly enhance combat effectiveness.
Similar to the Clocktower confrontation, maintain perpetual mobility when engaging Nemesis within the Disposal Center. His offensive repertoire includes numerous clearly telegraphed attacks; consistent movement combined with precise dodging maneuvers avoids most damage. Critical awareness: when Nemesis retreats significantly and crouches momentarily, he prepares to launch his tentacle arm projectile. Additional recognizable patterns include rearing upward for rapid leap assaults and slashing maneuvers with his secondary arm.
After activating the rail gun, you’ll notice three blue power cells in the chamber have shifted to red, signaling they need manual resetting. Attempting this while the Nemesis remains aggressive proves extremely hazardous—the process leaves you exposed for extended periods, creating vulnerability to devastating grab attacks that can instantly crush Jill. Your initial priority involves stunning the creature through strategic targeting.
The Nemesis displays prominent, throbbing orange sacs that serve as critical vulnerability zones. These weak spots respond exceptionally well to precise firearm damage, with handguns and magnums offering superior accuracy for consistent hits. Each sac typically requires only a few well-placed shots to rupture, and the environment provides generous ammunition reserves to support this approach.
While targeting the creature’s weaknesses, remain constantly aware of its offensive capabilities. Monitor both upper limbs and tentacle appendages, maintaining safe distance from their reach. When the boss slams both fists sequentially toward the ground, evade laterally to avoid the central impact zone. During tentacle elevation attacks, navigate through the gaps between them. The Nemesis’s substantial size and deliberate movements provide clear telegraphing of most attacks, allowing experienced players to anticipate and react accordingly.
The creature predominantly employs straightforward downward slams with its arms, making directional prediction relatively straightforward. Additionally, you must avoid acidic projectiles it launches, though these travel at manageable speeds with visible trajectories. Pro players recommend circling the perimeter while maintaining mid-range distance, as this positioning minimizes exposure to close-range grabs while providing clear attack visibility.
Successfully eliminating all weak points causes the Nemesis to collapse temporarily, creating a critical window for power cell restoration. On Standard difficulty, you typically have sufficient time to reset two cells on the right side before revival, but attempting the third often proves fatal if timing appears tight. Hardcore difficulty significantly reduces this recovery period, limiting you to just one cell per stun sequence. Always prioritize re-destroying weak points before addressing remaining cells.
Should your medical supplies or ammunition run low, thoroughly search the storage containers positioned immediately adjacent to the rail gun emplacement. These contain substantial handgun ammunition reserves, explosive grenades, and emergency first aid sprays. A common mistake involves overextending during stun phases—better to secure two safe resets than risk death for all three.
Reactivate the rail gun system, retrieve the weapon, and continue the engagement pattern until achieving final victory. Beyond the defeated Nemesis remains, ascend the ladder and inspect the left-side doorway to discover your concluding narrative element, the Suspicious Contract file.
While escaping Raccoon City marks a significant achievement, Resident Evil 3 offers substantial additional content. Completing the game on Hardcore unlocks Nightmare mode, which reorganizes enemy placements and item positions while increasing overall challenge. Conquering Nightmare then activates Inferno mode, escalating difficulty parameters even further. Many seasoned players consider these enhanced difficulty settings the definitive way to experience the Resident Evil 3 Remake.
The Bonuses screen Shop enables acquisition of new firearms and equipment that facilitate speedrun attempts and Records screen objective completion. Substantial additional content exists to extend your gameplay experience considerably.
Missing crucial items or locations? Our comprehensive Complete Guide provides detailed walkthroughs for all game segments, while our Weapons Unlock guide details optimal loadouts. For character optimization, consult our Class Guide to maximize your combat effectiveness.
Action Checklist
- Collect Hip Pouch from safe room immediately after elevator exit
- Secure Explosive A before descending into warehouse areas
- Eliminate Pale Head zombies with high-caliber weapons only
- Locate all three fuses while managing zombie dog encounters
- Retrieve Charle Doll from right shelf during corridor progression
- Collect Antigen Sample and prepare for zombie ambush in Lab A
- Craft acid rounds before server room exploration
- Solve vaccine temperature puzzle using Med-High-Low sequence
- Defeat three Hunters using acid round weakening strategy
- Prepare inventory with 10+ magnum rounds before Nemesis encounter
- Implement constant movement tactics during Disposal Center boss battle
- Target orange sac weak points with precision weapons
- Dodge attacks by watching arm movements and acid projectiles
- Reset power cells during stun phases according to difficulty level
- Collect Suspicious Contract file after victory
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