How to solve the Laboratory periodic table puzzle in Blue Prince

Conquer both intricate puzzles within Blue Prince’s Laboratory to unlock essential game progression.

The Laboratory in Blue Prince presents players with two interconnected challenges: the periodic table puzzle and the machine puzzle. These aren’t standalone obstacles but rather complementary tests that must be solved sequentially.

Understanding the relationship between these puzzles is crucial — you must first decipher the periodic table code to properly configure the electrical settings on the machine. This guide provides comprehensive strategies for solving both Laboratory puzzles efficiently, including detailed methods for obtaining the periodic table cipher and activating the Laboratory machinery.

Successfully navigating the periodic table challenge requires locating two critical components and understanding their relationship.

To solve the initial puzzle and gain insight for the subsequent machine challenge, you need to find both the code sheet (a numbered blank periodic table) and a complete periodic table reference. These items are strategically placed in opposite Laboratory corners to encourage thorough exploration.

The code document is positioned on the bulletin board adjacent to the lever-covered machine in one corner (referenced in the first image). The complete periodic table hangs in the diagonally opposite corner above a microscope-equipped workbench (shown in the second image). This spatial separation is intentional — many players miss one component by not exploring thoroughly.

Image: Dogubomb/Raw Fury via Polygon

Once you’ve collected both items, begin the decoding process. Systematically take the numbered sequence from the code sheet and cross-reference each number with the corresponding atomic symbol (the one- or two-letter abbreviations) on the complete periodic table. This methodical approach prevents transcription errors that commonly frustrate players.

After correctly matching all elements and inserting appropriate spacing, you’ll decipher the crucial instruction: PUSH THREE UP AFTER NINE. This command directly relates to the machine configuration in the next puzzle phase.

Image: Dogubomb/Raw Fury via Polygon

Before implementing the decoded instruction on the machine’s electrical controls, you must first activate the device by establishing a power connection.

To energize the Laboratory machinery in Blue Prince, establish a connection between a functioning Boiler Room and the Laboratory. This can be accomplished through direct room adjacency or utilizing the ceiling ductwork system. The duct network transmits steam power to any connected room equipped with ducts, creating flexible power routing options.

Several room types naturally support duct connections, including the Security Room, Passageway, and Archives. When planning your Laboratory layout, prioritize connecting these duct-compatible rooms to create efficient power pathways. The duct system offers significant advantages for complex mansion configurations where direct Boiler Room adjacency isn’t feasible.

Image: Dogubomb/Raw Fury via Polygon

Once powered, apply the deciphered instruction “PUSH THREE UP AFTER NINE” to the machine’s lever controls. This typically means adjusting the third lever upward position after configuring the ninth lever, though the exact implementation may vary based on your specific game progression. Proper execution unlocks advanced Laboratory functions critical for mansion exploration.

Image: Dogubomb/Raw Fury via Polygon

Mastering these Laboratory puzzles requires more than basic solutions — strategic optimization can significantly enhance your gameplay experience.

For experienced players, consider these advanced techniques: First, always prioritize Laboratory exploration early in your run — the rewards significantly impact subsequent mansion progression. Second, when decoding the periodic table, work systematically from left to right to avoid transposition errors that commonly plague rushed attempts.

The Laboratory puzzles typically take 8-12 minutes for new players but can be completed in under 5 minutes with practice. Common mistakes include missing one puzzle component due to inadequate room exploration or misinterpreting the duct connection requirements. Always verify that steam icons appear on connected rooms to confirm successful power transmission.

Successfully completing both Laboratory challenges unlocks critical gameplay elements that affect your overall Complete Guide progression. The solved machine often provides access to advanced equipment that complements your Weapons Unlock strategies and enhances your chosen Class Guide specialization.

No reproduction without permission：SeeYouSoon Game Club » How to solve the Laboratory periodic table puzzle in Blue Prince Master Blue Prince's Laboratory puzzles with step-by-step solutions for periodic table codes and machine power connections