Best Warframe Weapons To Use

TL;DR

  • Proboscis Cernos offers unparalleled crowd control with its tendril-pulling mechanics and area denial capabilities
  • Rubico Prime remains the gold standard for Eidolon hunting with superior critical stats and radiation damage optimization
  • Paracesis provides unique anti-Sentient capabilities and scales to level 40 with proper forma investment
  • Strategic modding with specific elemental combinations dramatically increases weapon effectiveness
  • Weapon acquisition requires understanding crafting trees and mission-specific farming strategies


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Warframe provides players command over biomechanical combat suits equipped with devastating arsenals to conquer adversaries throughout the vast Origin System. While Warframes possess unique abilities and powers to combat Grineer, Corpus, and Infested factions, your primary tools of destruction remain the weapon categories: primary firearms, secondary sidearms, and melee instruments. Every loadout configuration includes one selection from each weapon classification.

Celebrating over ten years since launch, Warframe now features an arsenal exceeding 500 weapons. Similar to other player-versus-environment titles like Destiny 2, Outriders, and Lost Ark, certain armaments stand out as community-endorsed essentials. This comprehensive guide examines must-acquire weapons that will accelerate your leveling progress, efficiently eliminate opposition, and ensure survival against the diverse threats inhabiting the Origin System.

Proboscis Cernos

The Proboscis Cernos represents an evolutionary bow design that launches projectiles generating energy tendrils to ensnare targets, apply continuous damage, and culminate in a destructive blast at the impact location. Crafting this weapon demands significant time investment through a multi-stage manufacturing process. To acquire the Proboscis Cernos, players must first construct the standard Cernos, then utilize that crafted weapon to produce the Mutalist Cernos variant, ultimately transforming that intermediate version into the final Proboscis iteration.

This primary weapon excels at eliminating clustered enemy formations effortlessly. Strategic deployment includes targeting security apparatus in Spy missions, where proximity detonations disable cameras without triggering guard alerts. The emanating tendrils not only drag adversaries into the damage zone but also penetrate defensive cover to strike concealed foes.

Ranked among the game’s premier bow options, the Proboscis Cernos eliminates precision aiming requirements. Players can maintain constant mobility through jumping, gliding, dodging, and rolling maneuvers while interspersing shots seamlessly. Incorporating modifications like Multishot combined with accelerated Fire Rate generates volleys of multiple arrows, each producing tendril networks concluding with explosive finales. Applying Toxic, Viral, and Blast elemental combinations alongside Amalgam Serration and Heavy Caliber modifications creates not only the most lethal bow available but also an exceptionally satisfying tactical instrument.

Rubico Prime

The standard Rubico sniper rifle delivers exceptional accuracy and devastating critical damage against enemy weak points, but its Prime variant elevates these capabilities substantially. With enhanced base Damage, Critical Chance percentages, Reload Speed, Fire Rate, and Status Chance compared to the non-Prime version, the Rubico Prime stands as the definitive long-range elimination tool.

Eidolon hunting constitutes a primary endgame activity where players confront massive Kaiju entities patrolling The Plains of Eidolon during nocturnal cycles. Community consensus identifies the Rubico Prime as the optimal armament for neutralizing these colossal adversaries. Precision targeting of Eidolon vulnerable spots with appropriate modifications like Point Strike, Vital Sense, Stormbringer combined with Hellfire generates catastrophic radiation damage, exploiting the creatures’ specific elemental vulnerability.

Integrating Vigilante Armaments with Split Chamber enables rapid successive strikes against Eidolon weak points. This weapon proves indispensable for dedicated Eidolon hunters and veterans progressing through The Steel Path difficulty. Installing the Deadeye Mod on your Warframe provides the optimal configuration when engaging Eidolon targets.

Paracesis

Spoiler alert: Ballas presents the Paracesis upon concluding the Chimera Prologue narrative questline. This distinctive weapon features an expanded maximum Rank progression to level 40 instead of the standard level 30 cap common to most Warframe armaments. Applying Forma increases the Paracesis maximum Rank by two levels per polarization, with five total polarization opportunities available. Each Rank enhancement boosts this melee instrument’s damage output specifically against Sentient enemies, and with Sentients ranking among the game’s most challenging adversary types, the Paracesis provides reliable countermeasures against these formidable opponents.

Stropha
Pyrana Prime
Kuva Nukor

Beyond the highlighted selections, several additional weapons deserve consideration for any comprehensive arsenal. The Stropha shotgun-pistol hybrid delivers massive burst damage with its charged projectile attacks, ideal for eliminating heavily armored targets. Pyrana Prime offers exceptional close-quarters firepower with its automatic shotgun pistol mechanics, while Kuva Nukor provides unparalleled status effect propagation with its chaining beam technology.

Action Checklist

  • Complete Chimera Prologue quest to obtain Paracesis melee weapon
  • Progress through Cernos crafting tree: Standard → Mutalist → Proboscis
  • Farm Rubico Prime components through relic cracking sessions
  • Optimize sniper mod configuration for Eidolon hunting with radiation damage
  • Apply five Forma to Paracesis to unlock level 40 maximum rank
  • Test weapon performance in Simulacrum before actual missions

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